Center for Genomically Engineered Organs

Mouse hippocampal neurons viewed with Expansion Microscopy

Mouse hippocampal neurons viewed with Expansion Microscopy
We are working to use the newly developed technique of Expansion Microscopy (ExM) to study our genomically engineered organoids at super-resolution. This image shows mouse hippocampal neurons, expressing Brainbow 3.0 delivered in viral form, that have been expanded ~4.5x linearly in each dimension after being processed with ExM.
(Image courtesy of the Boyden Lab.)